Synthetic Studies on Coenzyme Q10
β
Xiong-Jie Yu; Fen-Er Chen; Hui-Fang Dai; Xu-Xiang Chen; Yun-Yan Kuang; Bin Xie
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Article
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2005
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John Wiley and Sons
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German
β 103 KB
π 1 views
## Abstract A practical, highly stereoselective tenβstep synthesis of coenzyme Q~10~ (**1**) has been accomplished (overall yield __ca.__ 28%), starting from commercially available 2,3βdimethoxyβ5βmethylbenzoquinone (__Scheme__). The introduction of the first sideβchain isoprenyl group with (__E__)