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Coenzyme F430 from Methanogenic Bacteria: Oxidation of F430 Pentamethyl Ester to the Ni(III) Form

✍ Scribed by Bernhard Jaun

Publisher: John Wiley and Sons
Year: 1990
Tongue: German
Weight: 452 KB
Volume: 73
Category: Article
ISSN: 0018-019X
DOI: 10.1002/hlca.19900730818

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✦ Synopsis

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F430M, the pentamethyl ester of coenzyme F430, can be oxidized reversibly by one electron. The oxidation potential has been determined, and the electrolytically prepared oxidation product was characterized by its UVjVIS and ESR spectrum. The strongly anisotropic and nearly axial ESR spectrum is consistent with a S = ' / > species with the unpaired-electron spin density predominantly in a dZ2-type orbital of the central nickel ion. The properties of Ni(III)F430M are discussed in the context of two hypothetical mechanisms for the catalytic role of coenzyme F430 in methyl coenzyme M reductase, which catalyses the last step of methane formation in methanogenic bacteria.

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