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Codon 178 mutation in ethnically diverse Creutzfeldt-Jakob disease families

✍ Scribed by NIETO, A


Book ID
123185399
Publisher
The Lancet
Year
1991
Tongue
English
Weight
347 KB
Volume
337
Category
Article
ISSN
0140-6736

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Mutation of thePRNP gene at codon 211 in
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Creutzfeldt-Jakob disease (CJD) belongs to a group of chronic, progressive, neurodegenerative disorders that may be hereditary, infectious, or sporadic. Hereditary CJDs are associated with mutations in the PRNP gene on chromosome 20p12-pter. We report a family in which four patients developed classi