Cocoa procyanidins protect PC12 cells from hydrogen-peroxide-induced apoptosis by inhibiting activation of p38 MAPK and JNK

Apoptosis of mesenchymal stem cells indu

Apoptosis of mesenchymal stem cells induced by hydrogen peroxide concerns both endoplasmic reticulum stress and mitochondrial death pathway through regulation of caspases, p38 and JNK

✍ Hua Wei; Zongwei Li; Shengshou Hu; Xi Chen; Xiangfeng Cong 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 600 KB

Poor survival of mesenchymal stem cells (MSCs) compromised the efficacy of stem cell therapy for myocardial infarction. The increase of exogenous reactive oxygen species (ROS) in infracted heart is one of the important factors that challenged the survival of donor MSCs. In the study we aimed to eval