Cochrane Database of Systematic Reviews
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Shea, Beverley
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Article
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2013
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Wiley (John Wiley & Sons)
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English
โ 526 KB
## Background: Methotrexate (mtx) is a disease modifying antirheumatic drug (dmard) used as a first line agent for treating rheumatoid arthritis (ra). pharmacologically, it is classified as an antimetabolite due to its antagonistic effect on folic acid metabolism. many patients treated with mtx exp