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Cochlear function in mice with only one copy of the prestin gene

✍ Scribed by M. A. Cheatham; J. Zheng; K. H. Huynh; G. G. Du; J. Gao; J. Zuo; E. Navarrete; P. Dallos

Book ID: 110113571
Publisher: Cambridge University Press
Year: 2005
Tongue: English
Weight: 309 KB
Volume: 569
Category: Article
ISSN: 0022-3751
DOI: 10.1113/jphysiol.2005.093518

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## Abstract ## Objective To investigate whether heterozygosity for a loss‐of‐function mutation in the gene encoding the α1 chain of type XI collagen (__Col11a1__) in mice (chondrodysplasia, __cho__) causes osteoarthritis (OA), and to understand the biochemical and biomechanical effects of this mut