Cocaine is a potent hepatotoxin in mice. It is converted in the liver by a minor oxidative pathway to the active metabolite, norcocaine nitroxide. Previous studies have shown evidence of a lipid peroxidative mechanism of toxicity, including increased conjugated diene absorption by hepatic microsomal
Cocaine-induced hepatotoxicity
โ Scribed by John M. Porter; Marc S. Sussman; Gerald M. Rosen
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 139 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
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