✦ LIBER ✦

Cocaine-induced changes in time course of regional cerebral blood volume and transit time as determined by dynamic MR imaging

✍ Scribed by Ka-Loh Li; James N. Suojanen

Publisher: John Wiley and Sons
Year: 1995
Tongue: English
Weight: 411 KB
Volume: 5
Category: Article
ISSN: 1053-1807
DOI: 10.1002/jmri.1880050616

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

We examined cocaine‐mediated changes in regional cerebral blood volume (rCBV) and mean transit time (MTT) in central brain structures of rats using functional MR imaging techniques. Changes in MTT and rCBV in animals who had previously been given cocaine depended on the length of time between the last pretreatment injection and the acute injection and seemed to parallel cocaine‐mediated changes in extracellular dopamine concentrations.

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