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Cocaine binding sites in fetal rat brain: implications for prenatal cocaine action

โœ Scribed by Jerrold S. Meyer; Lauren P. Shearman; Lucille M. Collins; Robin L. Maguire


Publisher
Springer
Year
1993
Tongue
English
Weight
848 KB
Volume
112
Category
Article
ISSN
0033-3158

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In an effort to identify novel binding sites for cocaine and its analogs, we carried out binding studies with the high-affinity and selective ligand [ 125 I]RTI-121 in rat frontal cortical tissue. Very low densities of binding sites were found. Saturation analysis revealed that the binding was to bo