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Cocaine and metabolites in the hair of ancient Peruvian coca leaf chewers

✍ Scribed by Angela C Springfield; Larry W Cartmell; Arthur C Aufderheide; Jane Buikstra; Joyce Ho

Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
502 KB
Volume
63
Category
Article
ISSN
0379-0738

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✦ Synopsis

Cocaine and its metabolites, benzoylecgonine (BZE) and ecgonine methylester (EME), were found in hair samples from ancient Peruvian coca-leaf chewers dating back to AD 1000. Hair was analyzed by gas chromatography/mass spectrometry (GC/MS) to quantitate the concentrations. The two metabolites were found in higher concentration than the parent drug. The metabolite levels appear to be below that of modern cocaine abusers. Gender does not appear to be a factor in the incorporation of drug into hair.

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