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Cocaine- and amphetamine-regulated transcript peptide-immunoreactivity in adrenergic C1 neurons projecting to the intermediolateral cell column of the rat

✍ Scribed by Siok L Dun; Yee Kong Ng; G.Cristina Brailoiu; Eng Ang Ling; Nae J Dun

Book ID
117593370
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
726 KB
Volume
23
Category
Article
ISSN
0891-0618

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## Abstract Many sympathetic preganglionic neurons (SPN) in the intermediolateral cell column (IML) contain cocaine‐ and amphetamine‐regulated transcript (CART), but the function of these CART‐immunoreactive (IR) neurons is unknown. To test the possibility that CART might mark SPN involved in cardi

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Cocaine and amphetamine regulated transcript (CART) encodes a novel brain-enriched protein whose features are reminiscent of a neurotransmitter propeptide. We have now localized CART peptide(s) in the gastrointestinal tract by immunohistochemical methods. Polyclonal antisera raised to CART peptide 1