Cobalt(III) complexes of bidentate azotyrosine analogs

✍ Scribed by William I. White; J.Ivan Legg

• Book ID: 104105974
• Publisher: Elsevier Science
• Year: 1976
• Weight: 723 KB
• Volume: 6
• Category: Article
• ISSN: 0006-3061
• DOI: 10.1016/s0006-3061(00)80213-6

✦ Synopsis

As analogs for cobalt(III) complexes of bidentate azotyrosine in proteins, several cobalt(III) complexes of bidentate azophenok have been prepared and characterized. Tris(2-phenylazo-p-cresoiato)cobaltOII) was shown to be a poor model complex for this purpose; while cob&(W) complexes of either 2-phenylazo-p-cresol or Z-(4-carboxyphenylazo)-4,S&methylphenol with the linear tetradentate ligand etbylenediamine-N,N'-diacetic acid are very useful as model complexes. The complexes were characterized by magnetic susceptrbility, visible spectra and 'II NMR In the case of one of the mixed ligand complexes, a detailed description of the stereochemistry was possible. Comparisons of the spectral characteristics of metal complexes with bidentate and tridentate azophenols are made. These model studies are essential to a program involving the site specific modification of proteins with substitution inert metal ions.