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Cobalt-mediated alkylation of (4R) and (4S)-3-acetoacetyl-4-benzyloxazolidin-2-ones. Preparation of enantiopure diphenylmethyl-, 9-fluorenyl- and (1-adamantyl)glycines

✍ Scribed by Nicanor Gálvez; Marcial Moreno-Mañas; Adelina Vallribera; Elies Molins; Araceli Cabrero


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
232 KB
Volume
37
Category
Article
ISSN
0040-4039

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Preparation via Diastereoselective Hydro
✍ Günther Snatzke; Cristina Angeli; Enio Decorte; Flavio Moimas; Biserka Kojié-Pro 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 German ⚖ 834 KB

Hydrogenation of the ketone group in di-0-benzylderivative (8) of the known macrocyclic lactone zeralenone (7) using a novel chiral borane complex 3.BH3, prepared in situ, proceeded at lower temperatures with moderate diastereoselectivity ( -40%, d.e. at -60"). Unsaturated diastereomers 9 and 10 wer