Cobalt ion enhancement of 2-chloro[3H]adenosine binding to a novel class of adenosine receptors in brain: antagonism by calcium

Characterization of [3H]-N-[R-(2- Benzot

Characterization of [3H]-N-[R-(2- Benzothiazolyl)thio-2-propyl]-2-chloroadenosine ([3H]-NNC 21-0136) binding to rat brain: Profile of a novel selective agonist for adenosine A1 receptors

✍ Christian Thomsen; Jacob S. Valsborg; Christian Foged; Lars Knutsen 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 389 KB 👁 2 views

## thio-2-propyl]-2-chloroadenosine (NNC 21-0136) is a novel adenosine agonist with neuroprotectant properties in rodent models of focal and global ischemia that exhibits diminished cardiovascular side effects when compared to reference A 1 agonists [Sheardown et al., 1995]. NNC 21-0136 is shown t