Cobalt-Catalyzed Pyridine Syntheses from Alkynes and Nitriles

✍ Scribed by Priv.-Doz. Dr. Helmut Bönnemann

• Publisher: John Wiley and Sons
• Year: 1978
• Tongue: English
• Weight: 952 KB
• Volume: 17
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/anie.197805051

✦ Synopsis

Abstract

Soluble organocobalt catalysts permit selective formation of substituted pyridines under mild conditions in a single step: mono‐, di‐, and trisubstituted pyridines can be obtained at will in high conversions and high yields from nitriles and alkynes. Polynuclear derivatives such as bipyridines can also be prepared by this method.