Coating of Human Mesenchymal Cells in 3D Culture with Bioinorganic Nanoparticles Promotes Osteoblastic Differentiation and Gene Transfection

Stabilization of cellular properties and

Stabilization of cellular properties and differentiation mutilpotential of human mesenchymal stem cells transduced with hTERT gene in a long-term culture

✍ Guoping Huang; Qiang Zheng; Jie Sun; Chunjuan Guo; Jinfeng Yang; Rui Chen; Yulin 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 552 KB

## Abstract Human bone marrow mesenchymal stem cells (hMSCs) are promising candidates for cell therapy and tissue engineering. The life span of hMSCs during in vitro culture is limited. Human telomerase catalytic subunit (hTERT) gene transduction can prolong the life span of hMSCs and maintain thei