Coagulation disorders in cancer II. multiple myeloma
โ Scribed by Julio Sanchez-Avalos; Bernadette C. F. Soong; Sherwood P. Miller
- Publisher
- John Wiley and Sons
- Year
- 1969
- Tongue
- English
- Weight
- 969 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
I n a group of 100 unselected patients with disseminated malignancies, marked disturbances i n the coagulation and fibrinolytic systems were found. Mean silicone coagulation time was shortened, and fibrinogen levels were markedly elevated. Fibrinolysis activation, as manifested by plasma clot lysis,
A weakly positive but statistically significant association between HLA-Cw5 and myeloma has been reported in black patients. The authors attempted to determine whether immunoglobulin allotypes of the Cm series demonstrate any such association. They were identified in the sera of 29 black patients an
Seventy-four previously treated patients with multiple myeloma were treated with Amsacrine (m-AMSA) 120 mg/m2 every 3 weeks. A good response was observed in two patients (3%), and improvement was seen in three patients (4%). Severe toxicity was observed in 33% of patients who received three or more
In a phase II trial, 16 patients with relapsed refractory multiple myeloma received temsirolimus 25mg I.V. weekly until progression. One partial response and 5 minor responses were observed for a total response rate of 38%. The median time to progression was 138 days. Grade 3-4 toxicity included fat