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Co-transplantation of Liver Sinusoidal Endothelial Cells Promotes Repopulation of Transplanted Hepatocytes Following Hepatic Irradiation

โœ Scribed by Kabarriti, R.; Yaffe, H.; Zhang, W.; Asp, P.; Liu, L.; Patel, S.; Vainshtein, J.; Zhou, H.; Tome, W.A.; Guha, C.


Book ID
127315165
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
53 KB
Volume
90
Category
Article
ISSN
0360-3016

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Targeting of cells to specific tissues is critical for cell therapy. To study endothelial cell targeting, we isolated mouse liver sinusoidal endothelial cells (LSEC) and examined cell biodistributions in animals. To identify transplanted LSEC in tissues, we labeled cells metabolically with DiI-conju