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Co-operation between interleukin-1 and the fibrinolytic system in the degradation of collagen by articular chondrocytes

✍ Scribed by S.C. Cruwys; D.E. Davies; E.R. Pettipher


Book ID
117959407
Publisher
Nature Publishing Group
Year
1990
Tongue
English
Weight
892 KB
Volume
100
Category
Article
ISSN
0007-1188

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## Abstract Interleukin‐1 (IL‐1) and insulin‐like growth factor‐I (IGF‐I), which have opposing effects on matrix metabolism within articular cartilage, are thought to play prominent roles in the pathogenesis of osteoarthritis. To better understand the link between these anabolic (IGF‐I) and catabol