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Co-localization of the glial cell-line derived neurotrophic factor and its functional receptor c-RET in a subpopulation of rat dorsal root ganglion neurons

✍ Scribed by Takashi Honda; Masahide Takahashi; Yasuo Sugiura


Book ID
117478102
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
97 KB
Volume
275
Category
Article
ISSN
0304-3940

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Glial cell line-derived neurotrophic factor (GDNF) is a neurotrophic factor that influences the survival and function of several neuronal populations in the central (CNS) and peripheral nervous systems. The actions of GDNF are mediated by a multicomponent receptor complex composed of the tyrosine ki