Co-grinding with Cyclodextrin as a Nanoparticle Preparation Method of a Poorly Water Soluble Drug
โ Scribed by Yuichi Tozuka; Arpansiree Wongmekiat; Keiko Sakata; Kunikazu Moribe; Toshio Oguchi; Keiji Yamamoto
- Publisher
- Springer Netherlands
- Year
- 2004
- Tongue
- English
- Weight
- 105 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0923-0750
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๐ SIMILAR VOLUMES
The objective of this work was to demonstrate that the incorporation of sulfobutylether-beta-cyclodextrin, (SBE)(7M)-beta-CD, results in the complete and sustained release of a sparingly water-soluble drug, prednisolone (PDL) from controlled porosity-osmotic pump pellets (CP-OPP). PDL and CD were pr
Sustained-release formulations such as hydroxypropyl methylcellulose (HPMC)based hydrophilic matrix tablets of poorly water-soluble drugs often result in incomplete release because of the poor solubility and dissolution rate of the drug in the hydrophilic matrix. Sulfobutylether-b-cyclodextrins ((SB