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Co-electropolymerization of a viologen oligomer and lipoamide dehydrogenase on an electrode surface. Application to cofactor regeneration

✍ Scribed by Mihaela Draganoiu Leonida; Albert J. Fry; Susan B. Sobolov; Kamen I. Voivodov


Book ID
103983467
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
242 KB
Volume
6
Category
Article
ISSN
0960-894X

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✦ Synopsis


We report here a novel enzyme electrode obtained by electrochemically copolymerization of a redox enzyme with an oligomeric organic redox mediator on the surface of a glassy carbon electrode. This electrode serves as an efficient catalyst for the regeneration of the cofactor in enzymatic syntheses requiting NADH. The reaction shows a relatively short induction period and the rate of product formation is higher than for similar electrodes upon which the enzyme and redox mediator are physically trapped under a Nafion membrane.