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Co-cultures of hepatocytes with epithelial-like cell lines: Expression of drug-biotransformation activities by hepatocytes

✍ Scribed by M. Teresa Donato; José V. Castell; M. José Gómez-Lechón

Publisher
Springer
Year
1991
Tongue
English
Weight
906 KB
Volume
7
Category
Article
ISSN
0742-2091

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✦ Synopsis

by the 5th day in MS cells/hepatocyte co-cultures. The fact that the results of our work show the suitability of MS cells, an epithelialderived cell line, for improving the expression of biotransformation enzymes of cultured hepatocytes opens new possibilities of simplifying co-cultures for their use in drug-metabolism studies.

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