CNQX increases spontaneous inhibitory input to CA3 pyramidal neurones in neonatal rat hippocampal slices

Spontaneous release from mossy fiber ter

Spontaneous release from mossy fiber terminals inhibits Ni2+-sensitive T-type Ca2+ channels of CA3 pyramidal neurons in the rat organotypic hippocampal slice

✍ Christopher A. Reid; Shenghong Xu; David A. Williams 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 330 KB

## Abstract Mossy fibers (axons arising from dentate granule cells) form large synaptic contacts exclusively onto the proximal apical dendrites of CA3 pyramidal neurons. They can generate large synaptic currents that occur in close proximity to the soma. These properties mean that active conductanc