CMR2009: 4.01: Contrast-induced nephropathy after intravenous administration: fact or fiction?
✍ Scribed by R. Katzberg; R. Lamba
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 82 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1555-4309
- DOI
- 10.1002/cmmi.314
No coin nor oath required. For personal study only.
✦ Synopsis
collected in 24 LV sectors. A standard dose (5 mmol kg À1 ) of Teslascan was infused over 5 min and contrast enhancement was followed for up to 1 h. Results: A major finding was that a weak correlation between SWT and R 1 was greatly strengthened after infusion of Teslascan (Fig. ). R 1 values before infusion were 0.87 and 0.96 s À1 in infarcted and remote sectors, respectively. After Teslascan R 1 increments were 0.24 s À1 in infarcted but 0.38 s À1 in remote sectors. In eight patients R 1 mapping revealed graded changes between the LV sectors. In the remaining two patients no infarction or graded R 1 changes were found, indicating myocardial salvage by the previous PCI treatment. Conclusion: From this early pilot study we conclude that by multisectorial R 1 mapping and use of Mn-releasing contrast media it is possible to obtain more graded information about myocardial viability than the mere presence or absence of infarction. Thus with expected improvements in techniques and applications MEMRI may become a promising tool to monitor remodeling and therapy aimed at prevention or treatment of heart failure.