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Clusterin: A forgotten player in Alzheimer's disease

โœ Scribed by Tapio Nuutinen; Tiina Suuronen; Anu Kauppinen; Antero Salminen

Book ID
113506402
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
498 KB
Volume
61
Category
Article
ISSN
0165-0173

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Apolipoprotein J (clusterin) is a ubiquitous multifunctional glycoprotein capable of interacting with a broad spectrum of molecules. In pathological conditions, it is an amyloid associated protein, co-localizing with fibrillar deposits in systemic and localized amyloid disorders. In Alzheimer's dise