Clustered GATA repeats (Bkm sequences) on the human Y chromosome

✍ Scribed by J. Arnemann; Sibylle Jakubiczka; J. Schmidtke; Renate Schäfer; J. T. Epplen

• Publisher: Springer
• Year: 1986
• Tongue: English
• Weight: 780 KB
• Volume: 73
• Category: Article
• ISSN: 0340-6717
• DOI: 10.1007/bf00279090

✦ Synopsis

Sixty eight individual clones of a human Y chromosome cosmid library were screened for the presence of GATA repeats, the major component of Bkm-related DNA sequences. Nine cosmid clones were found to cross-hybridize. The sequence organization of the repetitive base quadruplet GATA was analyzed using synthetic oligonucleotide probes. Subclones of GATA-positive cosmid clones were used for chromosomal localization of the Y-derived DNA sequences thus revealing male-specificity or male-female homology.