## Abstract Tardive dystonia usually occurs with a delay after neuroleptic exposure in patients with major psychosis. A subgroup of patients, however, is given such medication for βmild depressionβ or βneurasthenia.β Tardive dystonia, in general, may respond favorably to pallidal deep brain stimula
Clozapine treatment of psychosis in patients with tardive dystonia: Report of three cases
β Scribed by Dr. Joseph H. Friedman
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 351 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0885-3185
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Among the tardive dyskinesia syndromes, dystonia can be the most difficult to treat. It may be severe to the point of being disabling, yet the patients may require antipsychotic medications for an even more disabling psychosis. Clozapine, an atypical neuroleptic drug that lacks extrapyramidal effects, may be the drug of choice for such patients. This report describes three patients with significant dystonia, previously disabled by their psychoses, who have been successfully manged with clozapine plus other agents for >3 years.
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