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Clozapine Protects Dopaminergic Neurons from Inflammation-Induced Damage by Inhibiting Microglial Overactivation

✍ Scribed by Hu, Xiaoming; Zhou, Hui; Zhang, Dan; Yang, Sufen; Qian, Li; Wu, Hung-Ming; Chen, Po-See; Wilson, Belinda; Gao, Hui-Ming; Lu, Ru-band; Hong, Jau-Shyong

Book ID
107381797
Publisher
Springer US
Year
2011
Tongue
English
Weight
657 KB
Volume
7
Category
Article
ISSN
1557-1890

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## Abstract Microglial activation is believed to play a pivotal role in the selective neuronal injury associated with several neurodegenerative disorders, including Parkinson's disease (PD) and Alzheimer's disease. We provide evidence that (βˆ’)‐epigallocatechin gallate (EGCG), a major monomer of gre