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Clozapine interaction with the M2 and M4 subtypes of muscarinic receptors

✍ Scribed by Pavel Michal; Michaela Lysı́ková; Esam E El-Fakahany; Stanislav Tuček


Book ID
114017284
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
149 KB
Volume
376
Category
Article
ISSN
0014-2999

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Human skin fibroblasts express m2, m4, a
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Previous studies have demonstrated that muscarinic acetylcholine receptors (mAChRs) are expressed by human skin fibroblasts (HSF). We have identified the molecular subtypes of these receptors by reverse transcriptionpolymerase chain reaction (RT-PCR), using m1-m5 subtype-specific primers. These expe