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Clostridium difficile—A continually evolving and problematic pathogen

✍ Scribed by Lisa F. Dawson; Esmeralda Valiente; Brendan W. Wren

Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
306 KB
Volume
9
Category
Article
ISSN
1567-1348

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To enhance the physical stability of Clostridium difficile toxoids A and B, screening for stabilizing compounds was performed. The screening of 30 GRAS compounds at various concentrations and in several combinations was performed in two parts. First, a high-throughput aggregation assay was used to s