Clostridial ADP-ribosyltransferases — Modification of low molecular weight GTP-binding proteins and of actin by clostridial toxins

Interaction of the low-molecular-weight

Interaction of the low-molecular-weight GTP-binding protein rap2 with the platelet cytoskeleton is mediated by direct binding to the actin filaments

✍ Mauro Torti; Alessandra Bertoni; Ilaria Canobbio; Fabiola Sinigaglia; Eduardo G. 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 238 KB 👁 2 views

The interaction of the low-molecular-weight GTP-binding protein rap2 with the cytoskeleton from thrombin-aggregated platelets was investigated by inducing depolymerization of the actin filaments, followed by in vitro-promoted repolymerization. We found that the association of rap2 with the cytoskele