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Closer to the Source: Notch and the Nature of Thymus-Settling Cells

✍ Scribed by Valerie P. Zediak; Ivan Maillard; Avinash Bhandoola

Book ID
116570488
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
97 KB
Volume
23
Category
Article
ISSN
1074-7613

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Transgenic mice expressing hK10 under the keratin K5 promoter display several alterations in the epidermis including decreased cell proliferation, and reduced susceptibility to tumor development. Given that K5 promoter is also active in the epithelial cells of the thymus, we explored the possible al