This study reports on the ability of poly(ethylene glycol) diacrylate (PEGDA) hydrogel scaffolds with pendant integrin-binding GRGDSP peptides (RGD-gels) to support the re-differentiation of cultured vascular smooth muscle cells (SMCs) toward a contractile phenotype. Human coronary artery SMCs were
✦ LIBER ✦
Close relation of arterial ICC-like cells to the contractile phenotype of vascular smooth muscle cell
✍ Scribed by Vladimír Pucovský; Maksym I. Harhun; Oleksandr V. Povstyan; Dmitri V. Gordienko; Ray F. Moss; Thomas B. Bolton
- Book ID
- 114778263
- Publisher
- Carol Davila University of Medicine Bucharest, Romania
- Year
- 2007
- Tongue
- English
- Weight
- 477 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1582-1838
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Poly(ethylene glycol) diacrylate (PEGDA) hydrogel scaffolds were engineered to promote contractile smooth muscle cell (SMC) phenotype via controlled release of heparin. The scaffold design was evaluated by quantifying the effects of free heparin on SMC phenotype, engineering hydrogels to provide con