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CLOSE LINKAGE OF HYPERVARIABLE MARKER DXS255 TO DISEASE LOCUS OF WISKOTT-ALDRICH SYNDROME

โœ Scribed by Basile, G.deSaint; Fraser, N.J.; Craig, I.W.; Arveiler, B.; Boyd, Y.; Griscelli, G.; Fischer, A.


Book ID
122499384
Publisher
The Lancet
Year
1989
Tongue
English
Weight
419 KB
Volume
334
Category
Article
ISSN
0140-6736

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The Wiskott-Aldrich syndrome: refinement
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The Wiskott-Aldrich syndrome (WAS) has previously been mapped to the proximal short arm of the X chromosome between the DXS14 and DXS7 loci. In this study, further segregation analysis has been performed using a newly identified WAS family as well as an additional marker probe, HOATL1. The results i

Linkage of Wiskott-Aldrich syndrome with
โœ Suzanne M. Cremin; Wenda L. Greer; Rebecca Bodok-Nutzati; Marianne Schwartz; Mon ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Springer ๐ŸŒ English โš– 453 KB

Linkage analysis was performed in 19 families segregating for the Wiskott-Aldrich syndrome (WAS) and in 1 family with X-linked thrombocytopenia using nine polymorphic DNA markers spanning the interval DXS7-DXS14. The results confirm close linkage of WAS to the DXS7, TIMP, OATL1, DXS255, DXS146, and