Close Contacts between Carbonyl Oxygen Atoms and Aromatic Centers in Protein Structures: π···π or Lone-Pair···π Interactions?

Lone pair ··· π interactions between wat

Lone pair ··· π interactions between water oxygens and aromatic residues: Quantum chemical studies based on high-resolution protein structures and model compounds

✍ Alok Jain; Venkatnarayan Ramanathan; Ramasubbu Sankararamakrishnan 📂 Article 📅 2009 🏛 Cold Spring Harbor Laboratory Press 🌐 English ⚖ 713 KB

## Abstract The π electron cloud of aromatic centers is known to be involved in several noncovalent interactions such as CH···π, OH···π, and π···π interactions in biomolecules. Lone‐pair (lp) ··· π interactions have gained attention recently and their role in biomolecular structures is being reco