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Cloning, Sequence, and Expression of Mouse Protoporphyrinogen Oxidase

✍ Scribed by Tamara A. Dailey; Harry A. Dailey; Peter Meissner; A.R.K. Prasad

Book ID
115565327
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
189 KB
Volume
324
Category
Article
ISSN
0003-9861

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A respiratory-defective mutant (C54) of Saccharomyces cerevisiae was found to have a phenotype consistent with a mutation in either mitochondrial protoporphyrinogen oxidase or ferrochelatase. The mutant is grossly deficient in hemes, accumulates protoporphyrin and is rescued by exogenous heme. The i