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Cloning, purification and biochemical characterization of HIV-2 reverse transcriptase (RT) and comparison with endogenous HIV-2 RT

โœ Scribed by G. Piras; E. Tramontano; M. Putzolu; R. Casula; P. La Colla


Book ID
113259252
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
52 KB
Volume
26
Category
Article
ISSN
0166-3542

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## Abstract It has been reported that a new pattern of mutations, E44D/A and/or V118I, in the reverse transcriptase (RT) gene of HIVโ€1 confers a moderate level of resistance to lamivudine in the absence of the M184V mutation. The prevalence of this mutational pattern was studied in HIVโ€1 isolates o