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Cloning, overexpression and characterization of Leishmania donovani squalene synthase

✍ Scribed by Prachi Bhargava; Kishore Kumar; Shailendra S. Chaudhaery; Anil K. Saxena; Uma Roy


Book ID
109332039
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
409 KB
Volume
311
Category
Article
ISSN
0378-1097

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The squalene synthase (SQS) gene encodes a key regulatory enzyme, farnesyl-diphosphate farnesyltransferase (EC 2.5.1.21), in sterol biosynthesis. The SQS1 gene was isolated from a subgenomic library of the industrially important yeast Yarrowia lipolytica, using PCR-generated probes. Probes were base

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