Cloning of the pig aminopeptidase N gene: Identification of possible regulatory elements and the exon distribution in relation to the membrane-spanning region

Nonrandom distribution of interspersed r

Nonrandom distribution of interspersed repeat elements in the BCR and ABL1 genes and its relation to breakpoint cluster regions

✍ Aaron R. Jeffs; Elisabeth Wells; Christine M. Morris 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 150 KB

## Abstract The Philadelphia translocation, t(9;22)(q34;q11), is the microscopically visible product of recombination between two genes, __ABL1__ on chromosome 9 and __BCR__ on chromosome 22, and gives rise to a functional hybrid __BCR‐ABL1__ gene with demonstrated leukemogenic properties. Breakpoi