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Cloning of the mRNA of overexpression in colon carcinoma-1: a sequence overexpressed in a subset of colon carcinomas

✍ Scribed by Laurence Pibouin; Jacqueline Villaudy; Didier Ferbus; Martine Muleris; Marie-Thérèse Prospéri; Yurgos Remvikos; Gérard Goubin


Book ID
114135289
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
802 KB
Volume
133
Category
Article
ISSN
0165-4608

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## Abstract ## BACKGROUND High concentrations of insulin‐like growth factor (IGF)‐I and IGF‐II have been demonstrated in human colonic adenocarcinomas and exert mitogenic effects through paracrine/autocrine interactions with the IGF‐I receptor (IGF‐IR). However, definitive studies of IGF‐IR expres