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Cloning of the amiloride-sensitive FMRFamide peptide-gated sodium channel

โœ Scribed by Lingueglia, Eric; Champigny, Guy; Lazdunski, Michel; Barbry, Pascal


Book ID
109794743
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
902 KB
Volume
378
Category
Article
ISSN
0028-0836

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Expression of Amiloride-Sensitive Sodium
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The amiloride-sensitive epithelial sodium channel (ENaC) mediates Na ุ‰ reabsorption in many epithelial tissues including the distal nephron, colon, lung, and secretory glands and plays an important role in pathophysiology of hypertension and cystic fibrosis. The ENaC is a multimeric integral membran