## Abstract PC3^TIS21/BTG2^ is the founding member of a family of genes endowed with antiproliferative properties, namely BTG1, ANA/BTG3, PC3B, TOB, and TOB2. PC3 was originally isolated as a gene induced by nerve growth factor during neuronal differentiation of rat PC12 cells, or by TPA in NIH3T3
✦ LIBER ✦
Cloning of PC3B, a Novel Member of the PC3/BTG/TOB Family of Growth Inhibitory Genes, Highly Expressed in the Olfactory Epithelium
✍ Scribed by Pasquale Buanne; Giuseppina Corrente; Laura Micheli; Antonella Palena; Patrizia Lavia; Corrado Spadafora; Madepalli Krishnappa Lakshmana; Alessandra Rinaldi; Sandro Banfi; Michæla Quarto; Alessandro Bulfone; Felice Tirone
- Book ID
- 115615203
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 460 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0888-7543
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Tob is a member of the PC3/ BTG1/Tob family of vertebrate tumor suppressor genes; its expression is known to inhibit proliferation of cells in vitro, but its possible roles during normal development have not been investigated previously. The present study concerns the structure and developmental exp