✦ LIBER ✦

Cloning of human anti-GM1 antibodies from motor neuropathy patients

✍ Scribed by Dr. Hugh J. Willison; Gary Paterson; Peter G. E. Kennedy; Jean Veitch

Publisher: John Wiley and Sons
Year: 1994
Tongue: English
Weight: 1005 KB
Volume: 35
Category: Article
ISSN: 0364-5134
DOI: 10.1002/ana.410350416

No coin nor oath required. For personal study only.

✦ Synopsis

Copyright L? 1994 by the American Neurological Association 471 sera. We describe the basic biological properties of these antibodies in the context of their putative role in disease pathogenesis.

📜 SIMILAR VOLUMES

Patterns of reactivity of human anti-GM1

Patterns of reactivity of human anti-GM1 antibodies with spinal cord and motor neurons

✍ Massimo Corbo; Angelo Quattrini; Alessandra Lugaresi; Maria Santoro; Norman Lato 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 747 KB

Human anti-GMI antibodies from patients with lower motor neuron disease or predominantly motor neuropathy recognize carbohydrate determinants shared by GM1 and related glycolipids and glycoproteins, but the identity of the antigens to which they bind in tissue is unknown. We examined the binding of

Anti-GM1 antibodies and impaired blood–n

Anti-GM1 antibodies and impaired blood–nerve barrier may interfere with remyelination in multifocal motor neuropathy

✍ Ryuji Kaji; Nobuyuki Hirota; Nobuyuki Oka; Nobuo Kohara; Tetsuya Watanabe; Takes 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 278 KB

Demyelinating symmetric motor polyneurop

Demyelinating symmetric motor polyneuropathy with high titers of anti-GM1 antibodies

✍ Erin K. O'Ferrall; Christopher M. White; Douglas W. Zochodne 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 344 KB

Polyclonal IgM anti-GM1 ganglioside anti

Polyclonal IgM anti-GM1 ganglioside antibody in patients with motor neuron disease and variants

✍ Edgar F. Salazar-Grueso; Mark J. Routbort; Jay Martin; Glyn Dawson; Raymond P. R 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 889 KB

Anti-GM1 ganglioside igm-antibodies pres

Anti-GM1 ganglioside igm-antibodies present in human plasma: Affinity and biological activity changes in a patient with neuropathy

✍ Roxana K. Mizutamari; Leonardo J. Kremer; Elizabeth A. Basile; Gustavo A. Nores 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 93 KB 👁 1 views

Low affinity anti-GM 1 IgM-antibodies are part of the normal repertoire of human plasma antibodies (Mizutamari et al.: J Neuroimmunol 50:215-220, 1994), a fact that is against the pathological role proposed for them in autoimmune diseases. Here we present evidence that these low affinity IgM-antibod

High affinity of anti-GM1 antibodies is

High affinity of anti-GM1 antibodies is associated with disease onset in experimental neuropathy

✍ Romina Comín; Nobuhiro Yuki; Pablo H.H. Lopez; Gustavo A. Nores 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 209 KB

## Abstract High antibody affinity has been proposed as a disease determinant factor in neuropathies associated with anti‐GM~1~ antibodies. An experimental model of Guillain‐Barré syndrome, induced by immunization of rabbits with bovine brain gangliosides or GM~1~, was described recently (Yuki et a