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Cloning of a human nucleoside transporter implicated in the Cellular uptake of adenosine and chemotherapeutic drugs

✍ Scribed by Griffiths, Mark; Beaumont, Nick; Yao, Sylvia Y. M.; Sundaram, Manickavasagam; Boumah, Christine E.; Davies, Anthony; Kwong, Francis Y. P.; Coe, Imogen; Cass, Carol E.; Young, James D.


Book ID
109926786
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
799 KB
Volume
3
Category
Article
ISSN
1078-8956

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Adenosine is a hydrophilic molecule that requires specialized transport proteins for permeation of cell membranes. Functional studies have identified two types of nucleoside transport processes: equilibrative bidirectional processes driven by chemical gradients and inwardly directed concentrative pr