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Cloning, localisation and functional expression of the human orthologue of the TREK-1 potassium channel

โœ Scribed by H.J. Meadows; C.D. Benham; W. Cairns; I. Gloger; C. Jennings; A.D. Medhurst; P. Murdock; C.G. Chapman

Publisher
Springer
Year
2000
Tongue
English
Weight
123 KB
Volume
439
Category
Article
ISSN
0031-6768

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## Abstract TREKโ€1 is a mechanosensitive member of the twoโ€pore domain potassium channel family (2PK+) that is also sensitive to lipids, free fatty acids (including arachidonic acid), temperature, intracellular pH, and a range of clinically relevant compounds including volatile anaesthetics. TREKโ€1