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Cloning and partial structure of the gene encoding human tissue inhibitor of metalloproteinases-3

✍ Scribed by Khalil Hammani; Patrick Henriet; Scott M Silbiger; Yves A Declerck

Book ID: 116133403
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 158 KB
Volume: 170
Category: Article
ISSN: 0378-1119
DOI: 10.1016/0378-1119(95)00864-0

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A complex interplay between enzymes involved in extracellular matrix formation and their inhibitors is thought to control organogenesis during mammalian development. Disturbance of this balance may result in a wide range of diseases, including macular degeneration, arthritis, and tumor metastases. I