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Cloning and high level expression of a synthetic gene for human basic fibroblast growth factor

✍ Scribed by Peter V. Milev; Oleg I. Georgiev; Plamen O. Tzarnoretchki; Asen A. Hadjiolov

Book ID: 119131807
Publisher: Elsevier Science
Year: 1992
Tongue: English
Weight: 666 KB
Volume: 22
Category: Article
ISSN: 0168-1656
DOI: 10.1016/0168-1656(92)90148-3

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## Abstract Basic fibroblast growth factor (bFGF) is a heparinbinding protein, expressing potent mitogenic and angiogenic properties. Elevated levels of bFGF have been identified in human gliomas and glioma cell lines, suggesting that bFGF expression is involved in the aberrant growth patterns asso