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Cloning and functional characterization of a cation–chloride cotransporter geneOsCCC1

✍ Scribed by Xiang-Qiang Kong; Xiu-Hua Gao; Wei Sun; Jing An; Yan-Xiu Zhao; Hui Zhang

Book ID
106498617
Publisher
Springer
Year
2011
Tongue
English
Weight
796 KB
Volume
75
Category
Article
ISSN
0167-4412

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Hepatic uptake of organic cations is essential for the metabolism and secretion of numerous endobiotics and drugs. Several hepatic organic cation transporters have been kinetically defined, yet have not been isolated or cloned. We have isolated a complementary DNA (cDNA) from both murine liver and k