## Abstract The innate immune system of mammals is able to detect bacteria when they infect local tissue or enter the blood stream, and initiate an immediate immune response. Prostaglandin (PG) E2 is considered as the most important link between the peripheral immune system and the brain. Due to fo
Cloning and expression of the rabbit prostaglandin EP2 receptor
✍ Scribed by Youfei Guan; Brett A Stillman; Yahua Zhang; André Schneider; Osamu Saito; Linda S Davis; Reyadh Redha; Richard M Breyer; Matthew D Breyer
- Publisher
- BioMed Central
- Year
- 2002
- Tongue
- English
- Weight
- 857 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1471-2210
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## Abstract Elevated levels of prostaglandins such as PGE~2~ in inflamed gingiva play a significant role in the tissue destruction caused by periodontitis, partly by targeting local fibroblasts. Only very few studies have shown that PGE~2~ inhibits the proliferation of a gingival fibroblast (GF) ce
## Abstract Prostaglandin E~2~ (PGE~2~) has been shown to promote the development of murine skin tumors. EP1 is 1 of the 4 PGE~2~ G‐protein‐coupled membrane receptors expressed by murine keratinocytes. EP1 mRNA levels were increased ∼2‐fold after topical treatment with 12‐__O__‐tetradecanoylphorbol
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